Factors Influencing Uremic Pruritus among Patients Undergoing Hemodialysis Therapy
DOI:
https://doi.org/10.59894/jpkk.v5i4.1039Keywords:
Hemodialysis Therapy, uremic pruritus, chronic kidney diseaseAbstract
Background: Uremic pruritus is a common dermatological complication experienced by patients with chronic kidney disease undergoing hemodialysis. This condition can decrease comfort, interfere with daily activities, and reduce quality of life. Aim: To determine the factors influencing uremic pruritus in hemodialysis patients.. Method: This quantitative study with a descriptive design was conducted in the Hemodialysis Unit of Dr. M. Djamil General Hospital, Padang. A total of 61 respondents were selected using purposive sampling based on inclusion criteria. Data were collected using a demographic characteristics questionnaire and a Skin Moisture Meter to measure skin moisture, then analyzed univariately to describe frequency distribution, percentage, and the mean value of each variable. Results: The majority of respondents were male (60.7%), had secondary education (60.7%), and were unemployed (60.7%). The average duration of hemodialysis was 32.95 months, the mean Blood Urea Nitrogen (BUN) level was 126.62 mg/dl, and the mean skin moisture value was 16.20, categorized as very dry. Conclusion: emodialysis patients in this study tended to have low skin moisture, which may exacerbate uremic pruritus. Demographic and clinical factors such as gender, education, occupation, duration of hemodialysis, BUN levels, and skin moisture should be considered in the management of uremic pruritus.
References
Agarwal, S. K., et al. (2018). Skin changes in chronic kidney disease. Seminars in Nephrology, 38(6), 581–592.
Arifa, S. I., Azam, M., Handayani, & Oktia, W. K. (2017). Faktor yang berhubungan dengan kejadian penyakit ginjal kronik pada penderita hipertensi di Indonesia. Jurnal Kesehatan Masyarakat Maritim, 13(4), 319–328.
Arjani, I. (2017). Gambaran kadar ureum dan kreatinin serum pada pasien gagal ginjal kronis (GGK) yang menjalani terapi hemodialisis di RSUD Sanjiwani Gianyar. Meditory : The Journal of Medical Laboratory, 4(2), 145–153. https://doi.org/10.33992/m.v4i2.64
Br Sembiring, F., & Ginting, A. (2022). Gambaran usia dengan kejadian pruritus uremik pada pasien gagal ginjal kronik di RSUP Haji Adam Malik Medan. Indonesian Trust Health Journal, 5(1), 1–5. https://doi.org/10.37104/ithj.v5i1.89
CDC. (2021). Chronic kidney disease in the United States, 2021. Cdc, 1, 1–6. https://www.cdc.gov/kidneydisease/publications-resources/ckd-national-facts.html%0Ahttps://www.cdc.gov/kidneydisease/publications-resources/2019-national-facts.html
Daryaswanti, P. I. (2018). Pengaruh kombinasi stimulasi kutaneus dan virgin coconut oil terhadap kelembaban kulit dan kualitas tidur pada pasien gagal ginjal kronik. In Advances in Nursing Science. Universitas Airlangga.
Daryaswanti, P. I. (2019). Gambaran tingkat kelembaban kulit pada pasien gagal ginjal kronik di ruang Hemodialisa RSUD Buleleng. Jurnal Ilmiah Kesehatan Keperawatan, 1(1), 44–51.
Fajriati, N., & Asri, S. (2020). pengaruh pemberian VCO terhadap pruritus pasien ggk on hd. Jurnal Kesehatan Kusuma Husada, 9(3), 35–42.
Fauziah, N., & Soelistyowati, E. (2018). Faktor yang mempengaruhi terjadinya pruritus pada klien gagal ginjal kronik yang menjalani hemodialisis di Rumah Sakit Islam Jemursari Surabaya. Angewandte Chemie International Edition, 6(11), 951–952., XI(2), 111–118. http://journal.poltekkesdepkes-sby.ac.id/index.php/KEP/article/view/1467/832
Goldust, M. (2021). Chronic kidney disease-associated pruritus. BMC Nephrology, 15(3), 1–15.
Kemenkes RI. (2017). Situasi penyakit ginjal kronik. In Pusat data dan kementrian kesehatan RI.
Liu, J., et al. (2017). Pathogenesis and treatment of uremic pruritus. Journal of Dermatological Science, 85(3), 282–289.
Mardhatillah, M., Arsin, A., Syafar, M., & Hardianti, A. (2020). Ksetahanan hidup pasien penyakit ginjal kronik yang menjalani hemodialisis di Rsup Dr. Wahidin Sudirohusodo Makassar. Jurnal Kesehatan Masyarakat Maritim, 3(1), 21–33. https://doi.org/10.30597/jkmm.v3i1.10282
Muliani, R., Vitniawati, V., & Rakhman, D. A. (2021). Effectiveness of olive oil with virgin coconut oil on pruritus grade scores among hemodialysis patients. International Journal of Advancement in Life Sciences Research, 4(4), 25–33. https://doi.org/10.31632/ijalsr.2021.v04i04.004
Odonmeta, B., Unuigbe, E., & Otene, C. (2016). Pruritus in patients on maintenance hemodialysis in Benin City, Edo State, Nigeria. Journal of Integrative Nephrology and Andrology, 3(4), 114. https://doi.org/10.4103/2394-2916.193498
Perwiraningtyas, P., & Sutriningsih, A. (2021). Hubungan lama terapi hemodialisa dengan pruritus pasien gagal ginjal kronis di Rumah Sakit Panti Waluya Malang. Jurnal Ilmiah Ilmu Kesehatan, 9(2), 197–207.
Rehman, I. U., Lai, P. S. M., Kun, L. S., Lee, L. H., Chan, K. G., & Khan, T. M. (2020). Chronic kidney disease-associated pruritus and quality of life in Malaysian Patients undergoing Hemodialysis. Therapeutic Apheresis and Dialysis, 24(1), 17–25. https://doi.org/10.1111/1744-9987.12862
Riskesdas. (2018). Riset kesehatan dasar nasional. In Riskesdas. https://www.litbang.kemkes.go.id/hasil-utama-riskesdas-2018/
Simonsen, E., Komenda, P., Lerner, B., Askin, N., Bohm, C., Shaw, J., Tangri, N., & Rigatto, C. (2017). Treatment of uremic pruritus: A systematic review. American Journal of Kidney Diseases, 70(5), 638–655. https://doi.org/10.1053/j.ajkd.2017.05.018
Stander, S., et al. (2020). Pathophysiology of pruritus in chronic kidney disease. Acta Dermato-Venereologica, 100(12), adv00113.
USRD. (2021). 2021 annual data report table of contents incidence , prevalence , patient characteristics , and treatment modalities.
Wulandari, E. (2019). Hubungan lama hemodialisa dengan kejadian pruritus uremik pada pasien GGK RSUD Dr. Hardjono Ponorogo. Jurnal Kesehatan Manarang, 5(1), 24–31. http://jurnal.poltekkesmamuju.ac.id/index.php/m
Yonathan, E. L., & Darmawan, H. (2021). Manifestasi dermatologik pada pasien gagal ginjal kronis. Tarumanagara Medical Journal, 3(2), 442–451. https://journal.untar.ac.id/index.php/tmj/article/view/11764
Young, T. A., et al. (2017). Impact of environmental factors on xerosis and pruritus in chronic kidney disease. Clinical Nephrology, 87(6), 318–324.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 yuza olsi rahmi
This work is licensed under a Creative Commons Attribution 4.0 International License.
All articles published by Jurnal Penelitian Keperawatan Kontemporer (JPKK), the authors hold the copyright under license Creative Commons Attribution License.
